This is an on-going problem for me. I have a blue & white 450 mhz G3, and I'm constantly unplugging the mouse and/or keyboard. 90% of the time, replugging them in will get them to work again, but occassionaly I'll lose both while a song is in play or record mode, and the only option is to reboot. Its a pain in the butt, and makes me look like a fool in front of clients. By the way, I do graphics work for my day gig, and I've NEVER had a mouse or keyboard drop out on me...not once. I'm sure its a USB problem, but it baffles me why it only happens with PTLE. I get less problems when I use the el cheapo MacAlly keyboard and mouse. The Apple "pro" model keyboard and mouse increase the frequency of dropouts. Good luck, and PLEASE post any solutions you come up with. regards, Dave Patteson